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phendc3  (MedChemExpress)


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    Structured Review

    MedChemExpress phendc3
    Stabilizers and destabilizers of rG4 structures affect ribosomal frameshifting of HDAC1 . The effect of a G4-stabilizing ligand <t>(PhenDC3,</t> A ) or a G4 destabilizer (TMPyP4, B ) on the HDAC1 frameshifting ratio. The red arrows and numbers indicate the decreased percentage. Data in this figure represent the mean ± SD ( n ≥ 3 biological replicates; * P < 0.05, ** P < 0.01, Student’s t- test). n.s . indicates not significant.
    Phendc3, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phendc3/product/MedChemExpress
    Average 94 stars, based on 4 article reviews
    phendc3 - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes"

    Article Title: RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes

    Journal: Nucleic Acids Research

    doi: 10.1093/nar/gkaf1481

    Stabilizers and destabilizers of rG4 structures affect ribosomal frameshifting of HDAC1 . The effect of a G4-stabilizing ligand (PhenDC3, A ) or a G4 destabilizer (TMPyP4, B ) on the HDAC1 frameshifting ratio. The red arrows and numbers indicate the decreased percentage. Data in this figure represent the mean ± SD ( n ≥ 3 biological replicates; * P < 0.05, ** P < 0.01, Student’s t- test). n.s . indicates not significant.
    Figure Legend Snippet: Stabilizers and destabilizers of rG4 structures affect ribosomal frameshifting of HDAC1 . The effect of a G4-stabilizing ligand (PhenDC3, A ) or a G4 destabilizer (TMPyP4, B ) on the HDAC1 frameshifting ratio. The red arrows and numbers indicate the decreased percentage. Data in this figure represent the mean ± SD ( n ≥ 3 biological replicates; * P < 0.05, ** P < 0.01, Student’s t- test). n.s . indicates not significant.

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    Image Search Results


    Stabilizers and destabilizers of rG4 structures affect ribosomal frameshifting of HDAC1 . The effect of a G4-stabilizing ligand (PhenDC3, A ) or a G4 destabilizer (TMPyP4, B ) on the HDAC1 frameshifting ratio. The red arrows and numbers indicate the decreased percentage. Data in this figure represent the mean ± SD ( n ≥ 3 biological replicates; * P < 0.05, ** P < 0.01, Student’s t- test). n.s . indicates not significant.

    Journal: Nucleic Acids Research

    Article Title: RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes

    doi: 10.1093/nar/gkaf1481

    Figure Lengend Snippet: Stabilizers and destabilizers of rG4 structures affect ribosomal frameshifting of HDAC1 . The effect of a G4-stabilizing ligand (PhenDC3, A ) or a G4 destabilizer (TMPyP4, B ) on the HDAC1 frameshifting ratio. The red arrows and numbers indicate the decreased percentage. Data in this figure represent the mean ± SD ( n ≥ 3 biological replicates; * P < 0.05, ** P < 0.01, Student’s t- test). n.s . indicates not significant.

    Article Snippet: Immediately after dropwise addition of the DNA–PEI mixture, cells were treated with 2 μM PhenDC3 (MedChemExpress, HY-15594A) or 2 μM TMPyP4 (MedChemExpress, HY-108477), with dimethylsulfoxide (DMSO) serving as the vehicle control.

    Techniques: